Zeolite - Centroteh

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Details about Zeolite
Zeolites are rare natural minerals of volcanic origin, arising out of four elements: earth, fire, water anid air. They are a product of several millennia of chemical process and natural reaction between vulcanic ash condensate and ocean water in specific geological conditions. Zeolites are minerals which have started to apear 100 million years ago, when volcanos emerged from the seas, splitting continents, creating mountains and forming present-day appearance of the planet Earth. During the eruption of volcanos, liquid lava and thick ash, in contact with sea water formed hard aluminosilicate lava, from
which, thousands of years later, zeolite formed. Variations of temperature, geographical locations and other conditions had effect on millennia long chemical reactions between volcanic ash, lava, water and air, which made many zeolites hava numerous differences in composition. There are many subgroups of zeolite, which is used u in different purposes in science, idustry, agriculture and building because of it's characteristic properties of strong ion exchange.
Subgoup called clinoptilolite, which has crystal molecular lattice was traditionally used as natural
cure in human medicine. Zeolite clinoptilolite has cage-like structure with strong negative charge,
which attracts and adsorbs heavy metals, dangerous carcinogenic toxins, organic poisons and other harmful supstances.
The beginning of zeolite medical application was based on it's exceptional biophysical properties and
ion exchange property, which enable simultaneous process of remineralization and efficient natural
For contemporary medical use zeolite clinoptilolite is subject to a unique process of tribomechanical
micronization and activation which multiplies its medicinal properties. Zeolite is 100% natural mineral
that the human body recognizes as its own substance. It is absolutely safe and non-toxic, no lethal or
toxic dose, no adverse contraindications, side effects or interactions with other pharmacological or
phytopharmacologic substances. Zeolite is not addictive, does not settle in organs and is fully
eliminated from the body.

Activation of zeolite clinoptlolite is achieved by specific technological process of micronization to
nanoscale particles, which are generally smaller than cells of human organism. Nano particles
contained in one gram of micronized clinoptilolite have a total area of 50,000 m2, and interspersed with
50 million km of filter microchannels. Goal of this method is micronization and activation, which allows
known mechanisms of action of zeolites as well as the capacity of its action in this technological
procedure to impressively multiply.
The activation process if clinoptilolite zeolite is fine micronization of nanoparticles, wherein the
method also performs the activation of nanoparticles. Thereby no change in the chemical composition
is caused, but changing certain physio-chemical properties enhances the electrostatic charge, the ion
exchange capacity, specific surface area, the liquid absorption capacity, and the interior of the crystal
structure of water is released. Significantly, the crystal ball during the activation process gets superficial
cracks and becomes active in its inner layer. Micronization increases specific surface area of minerals,
in this way increasing its overall size, and thus the ion exchange capacity. Nano-particles carry nutrients
into the cells, then remove residual products of metabolism from cells, and release free water to the cell
that is located within the crystal lattice, improving membrane potential and it’s tightness of harmful
agents, and regulate aicd-alkali status.
The development of science, especially medical science of the 21st century is largely determined by the
development of nanotechnology and topics of activated zeolite are becoming more relevant as they
touch the area of nanomedicine.

Quotes translation: Book of zeolite science and technology: “Application of zeolites in medicine”.
Effect of clinoptilolite as dietary composition in fattening animals, authors: Krešimir Pavelić and Mirko
Herrmann, Ruđer Bošković Institute, Zagreb
''Dietary supplementation with clinoptilolite diet is beneficial in fattening animals. In pigs fattened with
clinoptilolite diet, they have increased weight and were less prone to diseases than pigs fed a normal
diet. The animals have shown increased appetite, and regular and proper digestion, and also increase
the proportion of meat in relation to fat. Clinoptilolite actively adsorbs ammonia, carbon dioxide,
hydrogen sulfide and merkapante, and has a strong deodorizing effect. Also removes toxins and
creates changes in the enzymological and immunological reactions.
Cases are made of zeolite application in animal breeding industry. 27 days old piglets were fed during 4
weeks of natural clinoptilolite with a 2% share of the food, corrected with concentration factor, which
contributed to the trend of faster growth and more favorable ratio of fed-gained. Even when the diet was
later added to the nutrient solution, piglets have continued throughout the period of the experiment to
show clearly enhanced growth and more favorable ratio of fed-gained.
Clinoptilolite has also increased excretion of nitrogen in the feces and reduced the excretion of nitrogen
in the urine. It showed no effect on the stability of the protein. It follows that the clinoptilolite as a dietary
supplement for growing pigs altered excretion in the urine without affecting the stability of the protein.
16 weeks old chickens from three different litters were fed with 135 g of protein per kg, and with and
without 50 g clinoptilolite per kg. The sterile river sand was replaced by clinoptilolite in a controlled diet
to keep food isoenergetic. Significant changes were observed when feeding clinoptilolite, especially in
the number of hatched eggs per hen, shell thickness, the efficiency of feed utilization in digestion and
humidity of excrement. Between treatments no changes in digestion were observed; weight, age of first
laying hens, fruit weight, food intake, and the level of absorption of radioactive amino acids lysine and
methionine in the bloodstream.
Clinoptilolite as a supplement to diet significantly reduces the harmful effects of aflatoxin because of its
strong absorption properties of aflatoxin and zearalenone. It is estimated that clinoptilolite as a dietary
supplement in the values of 1.5% and 2.5%, reduces the harmful effects of 2.5 mg of pure aflatoxin in
broiler chicks. Aflatoxin treatment significantly reduced serum pure protein, protein, inorganic
phosphate, uric acid, cholesterol, hematrocite, red blood cells, the average physical volume,
hemoglobin, platelet count and monocytes and increases the number of white blood cells and
The addition of clinoptilolite in aflatoxin-diet significantly reduces its harmful effects and should be
helpful in the treatment of aflatoxin in poultry. Clinoptilolite as a supplement to the diet of 50 g per kg
significantly reduces the harmful effects of aflatoxin in growing Japanese quail 10-45 days of age.
Aflatoxin reduces food intake and body weight from the third week onwards, and the addition of
clinoptilolite to diet significantly reduces negative effects of aflatoxins related to the amount of food
Zeolites could have some influence on the properties of the egg. Clinoptilolite from Greece increased
the weight of egg whites and yolks. The beneficial effect of clinoptilolite on the weight of the egg and the
egg is independent of the age of the chickens and the type of diet.
Clinoptilolite shows a significant preventive effect in reducing radiocesium-137 in male chicks exposed
to contaminated feed. Reducing radiocesium in meat varied from 60-70%, and edible organs more than
50%.'' (Unquote)
Zeolite as a mineral of negative ion charge acts in the body biophysical and not chemically or
pharmacologically, and naturally, effectively and selectively detoxifies the body of positively charged
substances, heavy metals, radioactive metals, herbicides, pesticides, nitrosamines, aflatoxins,
radioactive substances, UV radiation, ammonia, nicotine, alcohol, chemotherapy and radiation therapy,
birth control pills and long-term medication, and other organic and chemical toxins. In the process of
organism detoxification zeolite also eliminated: the excess of acid and alkalizing the body in order to
prevent disease, and acidic environments: candidiasis, gout, rheumatoid arthritis, stomach pain and
intestinal inflammation etc; eliminates excess glucose and prevents diabetes mellitus and complications
of diabetes; adsorbed virus components and prevents the replication of viruses: herpes, hepatitis,
influenza, reduces oxidative stress and eliminate its harmful implications for the organism as a whole.
Zeolite at cell level releases nutrients and essential minerals that continue to have a positive effect in
the body, and so remineralises and feeds the organism.
Zeolite also releases the free water which is inside the crystal lattice, enhances cell membrane potential
and its impermeability to harmful agents, and regulates the acid-base status.
Natural zeolite has about 276 species, and considering the morphological structure they occur in three
basic forms: fibrous, leafy and crystalline. Zeolite clinoptilolite, which has a crystalline molecular
structure is suitable for human use.
Zeolites are rock, microporous silicate minerals by composition aluminosilicates, which usually contain
one or divalent cations: Na, K and Ca. As natural hydrated crystals with well-defined structures
containing AlO4 and SiO2 tetrahedra linked together by oxygen atoms. Aluminum silicate molecules of
ancient volcanic ash have formed a solid three-dimensional structures, such as honeycomb, which are
extremely important for explaining the medicinal properties of zeolite clinoptilolite.
Zeolite in medicine
Activated micronized zeolite clinoptilolite is used as the most effective natural detoxifier and is taken as
a preventive, but also as supportive medical therapy in many health problems and disorders. On the
justification of the use of zeolites as supportive therapy many traditional and contemporary anecdotal
experience suggest, scientifically based and evaluated in hundreds of available scientific and clinical

They are mold products (secondary metabolites) which have toxic effect on humans and animals, and
are found in grain, animal feed, hay, silage, and haylage.
Molds, and therfore mycotoxins are found everywhere in nature. Mold development occurs in the field,
and continues in warehouses, especially in feed which is mechanically damaged or not dry enough.
Molds decrease nutritional value in feed by degradation of easily digestable organic matter, and therfore
increase the risk of toksins which are excreted by molds. Strong known toxins are:

AFLATOXINS – mycotoxins which are found in various species of Aspergilus, in many types of human
and animal food. They are dangerous to young and pregnant animals, as well as to poultry. They are
excreted in milk of contaminated animal. They cause weaker growth in animals, diarrhea, lower milk
production, and act carcinogenic.

OHRATOXINS – metabolites of molds Aspergilus and Penicillium, they are also called „warehouse
molds“. They are found in grain and legumes. Strong humidity suits them, and they are found in corn
together with other mycotoxins – aflatoxins, zearalenon and trihotecenin. They cause inflammation of
the kidneys and liver ailments, and are excreted in milk, and create residue in tissue (meat) of animals
fed with contaminated feed.
Ohratoxins do not decompose by heat treatment.
Fuzariotoxins – they are a product of mold Fuzarium, and most common are earalenon and
rihotecenin, which are developed in the field
Zearalenons are estrogenic metabolites of Fuzaria mold, that animals menifest as false pursuit, vulva
and vagina edema, udder swelling, weigh of birth canal and rear bowel, miscarriage, weaker growth
and less milk production.
In feed for adult cattle it is allowed to give content of maximally 5 mg zearlenon/kg, and in feed for dairy
cows 3 mg/kg.
Zearalenons are excreted in milk five more days after feeding stops, and are equally carcinogenic as
Trihotecens – they can be created by many sorts of Fuzaria mold, as well as some other mold sorts.
They damage skin, mucous membranes of the digestive and reproductive organs, nervous system, liver
and other organs.
They are found in grain and in dried meat products.

Bacteria and mold are found in lareg number of feed, so they pose great threat to animal health, and to
people who use products of animal origin.
Suppression of molds and destroying mycotoxins in feed are usually not successful, and apart from that
the feed is of limited use because it is harmful to animal and human health. To fight bacteria and mold
some agents for conserving feed can be used, such as propionic acid or mixture of other acids (MICOFARM
and others).
For recovery of voluminously feed alkalis, ammonia and ZIBEA 70 (Feldhofer 1989) can be used.
Mycotoxins are very resistant and are hard to destroy physically or chemically because they stay
preserved in form of strong poisons.
Mycotoxins are not destroyed by silage.
How to treat mycotoxicosis?
Veterinary medicine has not provided a solution to this problem because there is no cure for

If you are fighting mycotoxins use our mycotoxin zeolite based adsorbents – Mineral Detox and Min-AZel
Plus D. They act so that during the ionic exchange within the zeolite crystal lattice essential
minerals (calcium, magnesium, natrium, potassium and others) are released in animal organism, and
mycotoxins and other harmful particles (heavy metals, radioactive particles, poisons) are bound within
the zeolite crystal lattice, and are excreted with excrement. Zeolites are natural minerals which apart
from ion exchange property have other beneficial effects for animal organism: they regulate pH of
animal organism, which supports the growth and development of positive micropopulation in the
digestive system of animals, increase reproduction and health of offspring, increase milk and meat
production and quality, prevent diarrhea, improves the health of the animals.

Filip Čale
Đurmanečki put 12
10000 Zagreb

GCC representative
villa no. 64
Al Bateen area, Abu Dhabi
United Arab Emirates

Filip Čale
Đurmanečki put 12
10000 Zagreb
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